Özgeçmiş
Prof. Dr. Hakan Yaralı

Dergi Yayınları


  • Bosch E, Bulletti C, Copperman AB, Fanchin R, Yarali H,  Petta CA, Polyzos NP, Shapiro D, Ubaldi FM, Garcia Velasco JA, Longobardi S, D’Hooghe T, Humaidan P,  on behalf of the Delphi TTP Consensus Group:  How time to healthy singleton delivery could affect decision making during infertility treatment. A Delphi Consensus.  Reprod Biomed Online (in press).
  • Papanikolaou EG, Yarali H, Timotheou E, Grynberg M, Zafeiratis O, Tournaye H et al. A Proof-of-Concept Clinical Trial of A Single Luteal Use of Long-Acting Gonadotropin-Releasing Hormone Antagonist Degarelix in Controlled Ovarian Stimulation for In Vitro Fertilization: Long Antagonist Protocol. Front Endocrinol (Lausanne) 2018;9:25.
  • Mumusoglu S, Yarali I, Bozdag G, Ozdemir P, Polat M, Sokmensuer LK, Yarali H. Time-lapse morphokinetic assessment has low to moderate ability to predict euploidy when patient- and ovarian stimulation-related factors are taken into account with the use of clustered data analysis. Fertil Steril 2017;107:413-21 e4.
  • Mumusoglu S, Ozbek IY, Sokmensuer LK, Polat M, Bozdag G, Papanikolaou E, Yarali H. Duration of blastulation may be associated with ongoing pregnancy rate in single euploid blastocyst transfer cycles. Reprod Biomed Online 2017;35:633-9.
  • Bozdag G, Polat M, Yarali I, Yarali H. Live birth rates in various subgroups of poor ovarian responders fulfilling the Bologna criteria. Reprod Biomed Online 2017;34:639-44.
  • Yarali H, Polat M, Mumusoglu S, Yarali I, Bozdag G. Preparation of endometrium for frozen embryo replacement cycles: a systematic review and meta-analysis. J Assist Reprod Genet 2016;33:1287-304.
  • Yarali H, Bozdag G, Sokmensuer LK, Mumusoglu S. Excellence in assisted reproductive technologies: clinical and laboratory perspectives. J Assist Reprod Genet 2016;33:1259-60.
  • Yarali H, Bozdag G, Polat M, Yarali I, Humaidan P. Spontaneous clinical pregnancy following GNRH agonist trigger for final oocyte maturation and freeze-all approach: a case report. Reprod Biomed Online 2016;32:233-6.
  • Polat M, Yarali I, Boynukalin K, Yarali H. In vitro fertilization for endometriosis-associated infertility. Womens Health (Lond) 2015;11:633-41.
  • Esinler I, Bozdag G, Esinler D, Lale KS, Yarali H. Luteal-long GnRH agonist versus flexible-multidose GnRH antagonist protocols for overweight and obese patients who underwent ICSI. J Obstet Gynaecol 2015;35:297-301.
  • Polat M, Bozdag G, Yarali H. Best protocol for controlled ovarian hyperstimulation in assisted reproductive technologies: fact or opinion? Semin Reprod Med 2014;32:262-71.
  • Polat M, Boynukalin FK, Yarali I, Yarali H. Bilateral ectopic pregnancy following ICSI. BMJ Case Rep 2014;2014.
  • Polat M, Boynukalin FK, Yarali I, Esinler I, Yarali H. Endometriosis is not associated with inferior pregnancy rates in in vitro fertilization: an analysis of 616 patients. Gynecol Obstet Invest 2014;78:59-64.
  • Polat M, Boynukalin FK, Yarali I, Erdogan BD, Bozdag G, Yarali H. Transient intrauterine fluid accumulation not due to hydrosalpinx or any identifiable pelvic pathology is not detrimental to IVF outcome. Arch Gynecol Obstet 2014;290:569-73.
  • Seyhan A, Ata B, Polat M, Son WY, Yarali H, Dahan MH. Severe early ovarian hyperstimulation syndrome following GnRH agonist trigger with the addition of 1500 IU hCG. Hum Reprod 2013;28:2522-8.
  • Ata B, Seyhan A, Polat M, Young Son W, Yarali H, Dahan M. Risk factors for ovarian hyperstimulation syndrome: relevance of the number of follicles, serum estradiol levels and the number of oocytes collected. Hum Reprod 2013;28:2595.
  • Ata B, Seyhan A, Polat M, Son WY, Yarali H, Dahan M. Reply: GnRHa trigger and modified luteal support with one bolus of hCG should be used with caution in extreme responder patients. Hum Reprod 2013;28:2594-5.
  • Yildiz BO, Bozdag G, Yapici Z, Esinler I, Yarali H. Prevalence, phenotype and cardiometabolic risk of polycystic ovary syndrome under different diagnostic criteria. Hum Reprod 2012;27:3067-73.
  • Tiras B, Korucuoglu U, Polat M, Zeyneloglu HB, Saltik A, Yarali H. Management of endometrial polyps diagnosed before or during ICSI cycles. Reprod Biomed Online 2012;24:123-8.
  • Tiras B, Korucuoglu U, Polat M, Saltik A, Zeyneloglu HB, Yarali H. Effect of air bubble localization after transfer on embryo transfer outcomes. Eur J Obstet Gynecol Reprod Biol 2012;164:52-4.
  • Tiras B, Korucuoglu U, Polat M, Saltik A, Zeyneloglu HB, Yarali H. Effect of blood and mucus on the success rates of embryo transfers. Eur J Obstet Gynecol Reprod Biol 2012;165:239-42.
  • Esinler I, Bozdag G, Arikan I, Demir B, Yarali H. Endometrioma </=3 cm in diameter per se does not affect ovarian reserve in intracytoplasmic sperm injection cycles. Gynecol Obstet Invest 2012;74:261-4.
  • Dursun P, Erkanli S, Guzel AB, Gultekin M, Tarhan NC, Altundag O et al. A Turkish Gynecologic Oncology Group study of fertility-sparing treatment for early-stage endometrial cancer. Int J Gynaecol Obstet 2012;119:270-3.
  • Bozdag G, Esinler I, Yarali H. Pretreatment with oral contraceptive pills does not influence the pregnancy rate in the long leuprolide acetate protocol. Gynecol Obstet Invest 2012;73:53-7.
  • Yildiz BO, Bozdag G, Otegen U, Harmanci A, Boynukalin K, Vural Z et al. Visfatin and retinol-binding protein 4 concentrations in lean, glucose-tolerant women with PCOS. Reprod Biomed Online 2010;20:150-5.
  • Yildiz BO, Bozdag G, Harmanci A, Otegen U, Boynukalin K, Vural Z et al. Increased circulating soluble P-selectin in polycystic ovary syndrome. Fertil Steril 2010;93:2311-5.
  • Yarali H, Bozdag G, Polat M, Esinler I, Tiras B. Intracytoplasmic sperm injection outcome of women over 39: an analysis of 668 cycles. Arch Gynecol Obstet 2010;281:349-54.
  • Tiras B, Polat M, Korucuoglu U, Zeyneloglu HB, Yarali H. Impact of embryo replacement depth on in vitro fertilization and embryo transfer outcomes. Fertil Steril 2010;94:1341-5.
  • Yarali H, Polat M, Bozdag G, Gunel M, Alpas I, Esinler I et al. TESE-ICSI in patients with non-mosaic Klinefelter syndrome: a comparative study. Reprod Biomed Online 2009;18:756-60.
  • Yarali H, Esinler I, Polat M, Bozdag G, Tiras B. Antagonist/letrozole protocol in poor ovarian responders for intracytoplasmic sperm injection: a comparative study with the microdose flare-up protocol. Fertil Steril 2009;92:231-5.
  • Bozdag G, Yarali H, Polat M, Esinler I, Tiras B, Ayhan A. ICSI outcome following conservative fertility sparing management of endometrial cancer. Reprod Biomed Online 2009;18:416-20.
  • Devroey P, Fauser BC, Diedrich K; Evian Annual Reproduction (EVAR) Workshop Group 2008. 
  • Collaborators (16) Alviggi C, Baart E, Barrat C, Bergh C, Broekmans F, Evers JL, Griesinger G, Keay S, Olivennes F, Serour G, Staessen C, Sunde A, Venetis C, Yarali H, Howles CM, Jenkins J.  Approaches to improve the diagnosis and management of infertility.  Hum Reprod Update 2009; 15: 391-408.
  • Bozdag G, Esinler I, Yarali H. The impact of endometrial thickness and texture on intracytoplasmic sperm injection outcome. J Reprod Med 2009;54:303-11.
  • Onderoglu LS, Yarali H, Gultekin M, Katlan D. Endometrial osseous metaplasia: an evolving cause of secondary infertility. Fertil Steril 2008;90:2013 e9-11.
  • Esinler I, Bozdag G, Yarali H. Impact of isolated obesity on ICSI outcome. Reprod Biomed Online 2008;17:583-7.
  • Esinler I, Aktas D, Otegen U, Alikasifoglu M, Yarali H, Tuncbilek E. CYP1A1 gene polymorphism and polycystic ovary syndrome. Reprod Biomed Online 2008;16:356-60.
  • Bozdag G, Basaran A, Cil B, Esinler I, Yarali H. An oocyte pick-up procedure complicated with pseudoaneurysm of the internal iliac artery. Fertil Steril 2008;90:2004 e11-3.
  • Bozdag G, Aksan G, Esinler I, Yarali H. What is the role of office hysteroscopy in women with failed IVF cycles? Reprod Biomed Online 2008;17:410-5.
  • Yildirir A, Aybar F, Kabakci G, Yarali H, Oto A. Heart rate variability in young women with polycystic ovary syndrome. Ann Noninvasive Electrocardiol 2006;11:306-12.
  • Yarali H, Bozdag G. An ongoing pregnancy after frozen thawed embryo transfer in a patient with Klinefelter's syndrome. Gynecol Obstet Invest 2006;62:165-7.
  • Esinler I, Bozdag G, Aybar F, Bayar U, Yarali H. Outcome of in vitro fertilization/intracytoplasmic sperm injection after laparoscopic cystectomy for endometriomas. Fertil Steril 2006;85:1730-5.
  • Dursun P, Demirtas E, Bayrak A, Yarali H. Decreased serum paraoxonase 1 (PON1) activity: an additional risk factor for atherosclerotic heart disease in patients with PCOS? Hum Reprod 2006;21:104-8.
  • Cevrioglu AS, Esinler I, Bozdag G, Yarali H. Assessment of endocervical and endometrial damage inflicted by embryo transfer trial: a hysteroscopic evaluation. Reprod Biomed Online 2006;13:523-7.
  • Bayar U, Demirtas E, Usubutun A, Basaran M, Esinler I, Yarali H. Ovarian adenomyoma following gonadotrophin treatment for infertility. Reprod Biomed Online 2006;13:676-9.
  • Esinler I, Bayar U, Bozdag G, Yarali H. Outcome of intracytoplasmic sperm injection in patients with polycystic ovary syndrome or isolated polycystic ovaries. Fertil Steril 2005;84:932-7.
  • Yarali H, Zeyneloglu HB. Gonadotrophin treatment in patients with polycystic ovary syndrome. Reprod Biomed Online 2004;8:528-37.
  • Yarali H, Bozdag G, Aksu T, Ayhan A. A successful pregnancy after intracytoplasmic sperm injection and embryo transfer in a patient with endometrial cancer who was treated conservatively. Fertil Steril 2004;81:214-6.
  • Ozcakar L, Yarali H. Ankylosing spondylitis: an impending restraint for gynecological interventions? Rheumatol Int 2004;24:123.
  • Gomel V, Yarali H. Surgical treatment of polycystic ovary syndrome associated with infertility. Reprod Biomed Online 2004;9:35-42.
  • Yildiz BO, Yarali H, Oguz H, Bayraktar M. Glucose intolerance, insulin resistance, and hyperandrogenemia in first degree relatives of women with polycystic ovary syndrome. J Clin Endocrinol Metab 2003;88:2031-6.
  • Yildirir A, Aybar F, Tokgozoglu L, Yarali H, Kabakci G, Bukulmez O et al. Effects of hormone replacement therapy on plasma homocysteine and C-reactive protein levels. Gynecol Obstet Invest 2002;53:54-8.
  • Yarali H, Yildiz BO, Demirol A, Zeyneloglu HB, Yigit N, Bukulmez O et al. Co-administration of metformin during rFSH treatment in patients with clomiphene citrate-resistant polycystic ovarian syndrome: a prospective randomized trial. Hum Reprod 2002;17:289-94.
  • Yarali H, Yildiz B. Metformin and FSH for induction of ovulation in women with polycystic ovary syndrome. Hum Reprod 2002;17:3007-8.
  • Yarali H, Bukulmez O. The effect of intramural and subserous uterine fibroids on implantation and clinical pregnancy rates in patients having intracytoplasmic sperm injection. Arch Gynecol Obstet 2002;266:30-3.
  • Yildirir A, Yarali H, Kabakci G, Aybar F, Akgul E, Bukulmez O. Hormone replacement therapy to improve left ventricular diastolic functions in healthy postmenopausal women. Int J Gynaecol Obstet 2001;75:273-8.
  • Yildirir A, Kabakci G, Yarali H, Aybar F, Akgul E, Bukulmez O et al. Effects of hormone replacement therapy on heart rate variability in postmenopausal women. Ann Noninvasive Electrocardiol 2001;6:280-4.
  • Yildirir A, Aybar F, Kabakci MG, Yarali H, Akgul E, Bukulmez O et al. Hormone replacement therapy shortens QT dispersion in healthy postmenopausal women. Ann Noninvasive Electrocardiol 2001;6:193-7.
  • Yarali H, Yildirir A, Aybar F, Kabakci G, Bukulmez O, Akgul E et al. Diastolic dysfunction and increased serum homocysteine concentrations may contribute to increased cardiovascular risk in patients with polycystic ovary syndrome. Fertil Steril 2001;76:511-6.
  • Bukulmez O, Yucel A, Yarali H, Bildirici I, Gurgan T. The origin of spermatozoa does not affect intracytoplasmic sperm injection outcome. Eur J Obstet Gynecol Reprod Biol 2001;94:250-5.
  • Bukulmez O, Yarali H, Gurgan T. The presence and extent of endometriosis do not effect clinical pregnancy and implantation rates in patients undergoing intracytoplasmic sperm injection. Eur J Obstet Gynecol Reprod Biol 2001;96:102-7.
  • Bukulmez O, Al A, Gurdal H, Yarali H, Ulug B, Gurgan T. Short-term effects of three continuous hormone replacement therapy regimens on platelet tritiated imipramine binding and mood scores: a prospective randomized trial. Fertil Steril 2001;75:737-43.
  • Bildirici I, Bukulmez O, Ensari A, Yarali H, Gurgan T. A prospective evaluation of the effect of salpingectomy on endometrial receptivity in cases of women with communicating hydrosalpinges. Hum Reprod 2001;16:2422-6.
  • Yarali H, Demirol A, Bukulmez O, Coskun F, Gurgan T. Laparoscopic high lateral transposition of both ovaries before pelvic irradiation. J Am Assoc Gynecol Laparosc 2000;7:237-9.
  • Yarali H, Bukulmez O, Gurgan T. Combined bilateral ectopic and intrauterine pregnancy following ovulation induction with the low-dose step-up protocol in a patient with polycystic ovary syndrome. Arch Gynecol Obstet 2000;264:37-8.
  • Bukulmez O, Yarali H, Yucel A, Sari T, Gurgan T. Intracytoplasmic sperm injection versus in vitro fertilization for patients with a tubal factor as their sole cause of infertility: a prospective, randomized trial. Fertil Steril 2000;73:38-42.
  • Yarali H, Bukulmez O, Gurgan T. Urinary follicle-stimulating hormone (FSH) versus recombinant FSH in clomiphene citrate-resistant, normogonadotropic,chronic anovulation: a prospective randomized study. Fertil Steril 1999;72:276-81.
  • Gurgan T, Bukulmez O, Yarali H, Tanir M, Akyildiz S. Serum and peritoneal fluid levels of IGF I and II and insulinlike growth binding protein-3 in endometriosis. J Reprod Med 1999;44:450-4.
  • Bukulmez O, Yarali H, Gurgan T. Total corporal synechiae due to tuberculosis carry a very poor prognosis following hysteroscopic synechialysis. Hum Reprod 1999;14:1960-1.
  • Yarali H, Gomel V, Uygur D, Onculoglu C, Gedikoglu G, Gurgan T. A comparative study of the effects of thrombin and electrodesiccation used for haemostasis on inflammation and adhesion formation. Hum Reprod 1998;13:1493-5.
  • Gurgan T, Yarali H, Urman B. ICSI for selected oocytes within a batch--save for the 2nd time around? Intracytoplasmic sperm injection. Fertil Steril 1998;70:1184-5.
  • Duran EH, Gurgan T, Gunalp S, Enginsu ME, Yarali H, Ayhan A. A logistic regression model including DNA status and morphology of spermatozoa for prediction of fertilization in vitro. Hum Reprod 1998;13:1235-9.
  • Gurgan T, Urman B, Yarali H, Duran HE. Follicle-stimulating hormone levels on cycle day 3 to predict ovarian response in women undergoing controlled ovarian hyperstimulation for in vitro fertilization using a flare-up protocol. Fertil Steril 1997;68:483-7.
  • Yarali H, Gomel V, Koop D, Jetha N. A new type of CO2 laser avoids power density loss due to absorption and the blooming effect by the CO2 gas environment. Hum Reprod 1996;11:677-9.
  • Gurgan T, Yarali H, Urman B, Dagli V, Dogan L. Uterine rupture following hysteroscopic lysis of synechiae due to tuberculosis and uterine perforation. Hum Reprod 1996;11:291-3.
  • Gurgan T, Urman B, Yarali H. Results of in vitro fertilization and embryo transfer in women with infertility due to genital tuberculosis. Fertil Steril 1996;65:367-70.
  • Gurgan T, Urman B, Yarali H. Adhesion formation and reformation after laparoscopic removal of ovarian endometriomas. J Am Assoc Gynecol Laparosc 1996;3:389-92.
  • Gurgan T, Yarali H, Urman B. Diagnosis of early tubal pregnancy by salpingoscopy. J Am Assoc Gynecol Laparosc 1995;2:217-8.
  • Gurgan T, Urman B, Yarali H, Kisnisci HA. The results of in vitro fertilization-embryo transfer in couples with unexplained infertility failing to conceive with superovulation and intrauterine insemination. Fertil Steril 1995;64:93-7.
  • Yarali H, Zahradka BF, Gomel V. Hyaluronic acid membrane for reducing adhesion formation and reformation in the rat uterine horn. J Reprod Med 1994;39:667-70.
  • Yarali H, McComb PF, Lee NH. Evaluation of the sites of ectopic pregnancies subsequent to reconstructive tubal surgery. Hum Reprod 1994;9:90-1.
  • Yarali H, Gurgan T, Erden A, Kisnisci HA. Colour Doppler hysterosalpingosonography: a simple and potentially useful method to evaluate fallopian tubal patency. Hum Reprod 1994;9:64-6.
  • Gurgan T, Yarali H, Urman B. Laparoscopic treatment of polycystic ovarian disease. Hum Reprod 1994;9:573-7.
  • Gurgan T, Urman B, Yarali H, Aksu T, Kisnisci HA. Salpingoscopic findings in women with occlusive and nonocclusive salpingitis isthmica nodosa. Fertil Steril 1994;61:461-3.
  • Yarali H, Fleige-Zahradka BG, Yuen BH, McComb PF. The ascites in the ovarian hyperstimulation syndrome does not originate from the ovary. Fertil Steril 1993;59:657-61.
  • Gurgan T, Zeyneloglu H, Urman B, Develioglu O, Yarali H. Pelvic-peritoneal tuberculosis with elevated serum and peritoneal fluid Ca-125 levels. A report of two cases. Gynecol Obstet Invest 1993;35:60-1.
  • Gurgan T, Urman B, Aksu T, Yarali H, Kisnisci HA. Fluid accumulation in the uterine cavity due to obstruction of the endocervical canal in a patient undergoing in vitro fertilization and embryo transfer. J Assist Reprod Genet 1993;10:442-4.
  • Fluker MR, Yarali H, Yuen BH. Ovarian response in World Health Organization group II anovulatory women during consecutive human menopausal gonadotropin cycles. J Reprod Med 1993;38:839-42.
  • Gurgan T, Urman B, Aksu T, Yarali H, Develioglu O, Kisnisci HA. The effect of short-interval laparoscopic lysis of adhesions on pregnancy rates following Nd-YAG laser photocoagulation of polycystic ovaries. Obstet Gynecol 1992;80:45-7.
  • Gomel V, Yarali H. Infertility surgery: microsurgery. Curr Opin Obstet Gynecol 1992;4:390-9.
  • Gurgan T, Kisnisci HA, Yarali H, Develioglu O, Zeyneloglu H, Aksu T et al. Evaluation of the functional status of the fallopian tubes in unexplained infertility with radionuclide hysterosalpingography. Gynecol Obstet Invest 1991;32:224-6.
  • Gurgan T, Kisnisci HA, Yarali H, Caner B, Aksu T, Gunalp S et al. Radionuclide hysterosalpingography. A simple and potentially useful method of evaluating tubal patency. J Reprod Med 1991;36:789-92.
  • Gurgan T, Kisnisci H, Yarali H, Develioglu O, Zeyneloglu H, Aksu T. Evaluation of adhesion formation after laparoscopic treatment of polycystic ovarian disease. Fertil Steril 1991;56:1176-8.
  • Gurgan T, Kisnisci H, Yarali H, Aksu T, Zeyneloglu H, Develioglu O. The value of human menopausal gonadotropin treatment in patients with unexplained infertility. Int J Gynaecol Obstet 1991;35:327-30.
  • Ayhan A, Yarali H, Develioglu O, Uren A, Ozyilmaz F. Prognosticators of second-look laparotomy findings in patients with epithelial ovarian cancer. J Surg Oncol 1991;46:222-5.
  • Ayhan A, Yarali H, Ayhan A. Endometrial carcinoma: a pathologic evaluation of 142 cases with and without associated endometrial hyperplasia. J Surg Oncol 1991;46:182-4.
  • Ayhan A, Tuncer ZS, Yarali H. Complications of radical hysterectomy in women with early stage cervical cancer: clinical analysis of 270 cases. Eur J Surg Oncol 1991;17:492-4.
  • Ayhan A, Akarin R, Develioglu O, Yarali H, Kucukali T, Bilgin F. Borderline epithelial ovarian tumours. Aust N Z J Obstet Gynaecol 1991;31:174-6.
  • Gurgan T, Kisnisci H, Yarali H, Aksu T, Zeyneloglu H, Develioglu O. Serum and peritoneal fluid CA-125 levels in early stage endometriosis. Gynecol Obstet Invest 1990;30:105-8.
  • Durukan T, Urman B, Yarali H, Arikan U, Beykal O. An abdominal pregnancy 10 years after treatment for pelvic tuberculosis. Am J Obstet Gynecol 1990;163:594-5.
  • Ayhan A, Yarali H, Urman B, Yuce K, Gunalp S, Ayhan A et al. Comparison of clinical and surgical-pathologic staging in patients with endometrial carcinoma. J Surg Oncol 1990;43:33-5.
  • Ayhan A, Yarali H, Diker I, Urman B, Develioglu O. Digoxin-like immunoreactive substance and preterm labor. Gynecol Obstet Invest 1990;30:75-7.
  • Ayhan A, Urman B, Yarali H, Yuce K, Ayhan A. Predictors of recurrent disease after negative second-look laparotomy for epithelial ovarian cancer. J Surg Oncol 1990;44:119-21.
  • Ayhan A, Akkok E, Urman B, Yarali H, Dundar S, Kirazli S. Beta-thromboglobulin and platelet factor 4 levels in pregnancy and preeclampsia. Gynecol Obstet Invest 1990;30:12-4.
  • Ayhan A, Yarali H, Urman B, Gunalp S, Yuce K, Ayhan A et al. Lymph node metastasis in early endometrium cancer. Aust N Z J Obstet Gynaecol 1989;29:332-5.